Fri Sep 15 2023

20 articles - From Friday Sep 08 2023 to Friday Sep 15 2023

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Guidelines

Guidelines and related publications, position statements, white papers, technical reviews, consensus statements, etc…


Meta-analysis

meta-analyses and systematic reviews

Am J Clin Nutr

The Effectiveness of Medical Nutrition Therapy Provided by a Dietitian in Adults with Prediabetes: A Systematic Review and Meta-Analysis.

In adults with prediabetes, MNT was effective in improving glycemic outcomes, anthropometrics, blood pressure, and most lipid levels. However, most studies had risk of bias due to the randomization process or deviations from intended interventions. Conclusions MNT plays a key role in improving cardiometabolic risk factors in adults with prediabetes. Registration id and url ID #351421;

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J Crohns Colitis

Prevalence of hepatobiliary manifestations in inflammatory bowel disease: a GRADE assessed systematic review and meta-analysis on more than 1.7 million patients.

This study summarizes the prevalence and importance of different hepatic manifestations in IBD patients. These findings are crucial for the management of EIMs, especially hepatic manifestations, in IBD patients.

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Temporary Faecal Diversion for Refractory Perianal and/or Distal Colonic Crohn's Disease in the Biologic Era: An Updated Systematic Review with Meta-Analysis.

In the biologic era, temporary FD for refractory perianal and/or distal colonic CD improves symptoms half the patients, and bowel continuity can be successfully restored in a quarter of patients.

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Liver Transpl

Treatment strategies of hepatic artery complications after pediatric liver transplantation: A systematic review.

Despite various treatment methods, HAT after pLT remains a significant issue that has profound effects on the patient and graft survivals. Current evidence is insufficient to determine the most effective treatment for preventing graft failure.

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Original articles

RCT, clinical trials, retrospective studies, etc…

Am J Clin Nutr

Dietary greenhouse gas emissions and diet quality in a cross-sectional study of Swedish adolescents.

Food choices and dGHGE per calorie differ by sex in adolescents. Thus, intervention strategies to improve dietary sustainability need to be tailored differently to females and males. Diet quality should also be considered when promoting reduced GHGE diets.

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Inflamm Bowel Dis

Characterization of the Gut Microbiota and Mycobiota in Italian Pediatric Patients With Primary Sclerosing Cholangitis and Ulcerative Colitis.

We describe the gut microbiota and mycobiota dysbiosis associated to PSC-UC disease. Our results evidenced a gut imbalance, with the reduction of gut commensal microorganisms with stated anti-inflammatory properties (ie, Akkermansia, Bacteroides, Parabacteroides, Oscillospira, Meyerozyma, and Malassezia) and the increase of pathobionts (ie, Streptococcus, Saccharomyces, and Debaryomyces) that could be involved in PSC progression. Altogether, these events may concur in the pathophysiology of PSC in the framework of UC.

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Expression of Circulating let-7e and miR-126 May Predict Clinical Remission in Patients With Crohn's Disease Treated With Anti-TNF-a Biologics.

These results provide evidence that expression levels of circulating let-7e and miR-126 at baseline may predict clinical remission in CD patients treated with anti-TNF-a biologics.

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Racial and Ethnic Disparities in Patients With Inflammatory Bowel Disease: An Online Survey.

BIPOC/H patients with IBD had worse clinical disease, lower HRQOL scores, had more medication concerns, had less access to specialists, had less social and emotional support, and used emergency department services more often than W/NH patients.

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J Crohns Colitis

Mitigating the risk of Tofacitinib-induced adverse events in the elderly population with Ulcerative Colitis.

Modulation of induction dose and anti-thrombotic therapy may have contributed to prevent cardiologic events and thromboembolism. The introduction of zoster vaccine virtually eliminated zoster risk after the first cases. Potential malignancies deserve a careful work-up of older patients before treatment start.

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Prospective Observational Evaluation of the Time-Dependency of Adalimumab Immunogenicity and Drug Concentration in Ulcerative Colitis Patients: the POETIC II Study.

Loss of response to adalimumab therapy was significantly more common in the Ulcerative Colitis compared to the Crohn's disease cohort and was driven by a higher rate of non-immunogenic, pharmacodynamic parameters.

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Validation of the IBD-Control Questionnaire across different sociodemographic and clinical subgroups: Secondary analysis of a nationwide electronic survey.

IBD-Control-8 is a psychometrically robust scale which can be used across a range of populations. It offers a quick, reliable and valid method of assessing patient-perceived control. The construct of "control" includes traditional HRQoL and a novel domain relating to treatment perception.

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Liver Transpl

Early steroids after paediatric liver transplantation protect against T-cell mediated rejection -results from the ChilSFree study.

Adjunctive steroid therapy after pLT leads to earlier suppression of the post-pLT pro-inflammatory response and significantly reduced rejection rates during the first year after pLT (15.9%). 65% of patients initially treated without steroids remain steroid free over the first 12 months without rejection.

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Primary sclerosing cholangitis and other risk factors for post-transplant lymphoproliferative disease after liver transplantation in adults.

The yearly PTLD incidence was higher in the first year than in the later years after LT (2.4%/year vs 0.6%/year) for PSC but not for other indications (0.16%/year). In EBV seronegative recipients, PTLD occurred earlier after LT, while in the 97% seropositive recipients it could occur very late after LT.

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Pancreatology

Greater cost without greater benefit: The need to refine transfer criteria for patients with severe acute pancreatitis.

Transferred patients have greater burden of illness and cost of care without evidence of improved outcomes in the management of SAP regardless of procedural intervention. Transfer criteria for patients with SAP must be further refined to reduce unnecessary transfers.

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Reviews&Editorials

Plenty of the editorials are available as full text through the publisher website using the provided link

Inflamm Bowel Dis

Think Again Before Resecting an Organ: Appendectomy or Endoscopic Retrograde Appendicitis Therapy?

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Miscellaneous

misc publications eg case reports, tools of the trade, images of the month, etc…

Inflamm Bowel Dis

Revisiting the Risk of Hospital Readmission in Severe Ulcerative Colitis.

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J Crohns Colitis

Lémman Index in pediatric Crohn's disease - evidence is accumulating.

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Liver Transpl

Letter to the Editor: Blocked drain switch -- hepatic venous outflow obstruction.

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Reply: Blocked drain switch - hepatic venous outflow obstruction.

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Letters&Replies

Letters to the editors and authors’ replies

Am J Clin Nutr

Cooking Skills: Essential for the Food is Medicine Movement.

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